Scomberoides lysan fish showing multiple circumscribed hyperosteoid tissue in the neural spines (arrow) compared with the normal fish (lower photo).
Skeleton of Scomberoides lysan showing two hyperosteoid balls- shaped masses (arrow) in the neural spine; attached to the vertebrae and covered with delicate and glistening fibrous capsule with red dots of congested blood capillaries on its surface.
Hyperostoid tissue of variable sizes in both neural and haemal spines.
Radiographic image of hyperosteoid tissue with variable degrees of calcification intensities; note the decreased calcification intensity in the upper small sized osteoid mass in comparison to the lower larger masses (arrows).
Cross section in the hyperosteoid tissue showing central area of greasy calcified substance (c), granular in nature (g); bounded by fibrous capsule (f).
Normal Pomacanthus sextriatus fish without hyperostosis.
Pomacanthus sextriatus fish with multiple hyperosteoid circumscribed masses attached to neural spines and not attached to the vertebrae (arrows).
Figures 8-13.Histopathological section of hyperosteoid mass in acellular bony tissue of the spines showing: 8. External layer of periosteal tissue and thin layer of fibrous connective tissue capsule (f) followed by osteoid tissue (ot) with areas of empty spaces underneath. 9. The fibrous capsule containing congested blood vessel (co) and dilated lymph vessel (lv) surrounded by edema (e); the hyperosteoid tissue penetrated with the periosteal tissue (arrows). 10. Hyperostoid bony tissue surrounded by periosteal and fibrous connective tissue (f) and focal area of hemorrhage (h). 11. Hyperostoid bony tissue with prominent blue colored areas of calcification (ca) and prominent interlacing empty spaces (es). 12. Acellular calcified hyperosteoid tissue (ca) showing areas of hemorrhage in the surrounding empty spaces (es). 13. Multiple empty spaces (es) with variable sizes in the acellular hyperosteoid tissue.
